Time points Baseline to HFD 5 months   HFD 5 to 7 months  
Mouse strain WT mice Cpt1b+/- mice WT mice Cpt1b+/- mice
Body weight > >
Lean mass > =
Fat mass > >
Glucose tolerance = N/A N/A
Insulin sensitivity = ↓↓
Insulin signaling integrity Skeletal muscle < >
Liver < <  
Heart < <
Fat > >
Lipid metabolites in skeletal muscle NEFA = =
TAG = =  
C4-OH acylcarnitine = <
C18, C22:1-ceramide N/A <
Table 1: Summary of phenotypic changes during high fat diet-fed condition. =indicates similar trend, <indicates increased in Cpt1b+/- mice, >indicates decreased in Cpt1b+/- mice, ↓ indicates decreases during designated period in that strain.