A1C=glycated hemoglobin; DPP-4i=dipeptidyl peptidase-4 inhibitor; GLP-1-RA=glucagon-like peptide–1 receptor agonist; MET=metformin; SU=sulfonylurea; TZD=thiazolidinedione.

Figure 1: American Diabetes Association/European Association for the Study of Diabetes general recommendations for pharmacotherapy. Adapted from Inzucchi et al [11]. Permission pending