| pioglitazone |
baseline |
3 months |
12 months |
| Body mass index (kg/m2) |
22 ± 2.3 |
22.5 ± 2.2** |
23.4 ± 2.6*** |
| Waist circumference (cm) |
84.4 ± 7.4 |
85.9 ± 7.4* |
87.7 ± 8.5** |
| HbA1c (%) |
7.9 ± 1.7 |
7.4 ± 1.7** |
7.1 ± 1.2*** |
| DPP-4 (ng/mL) |
774 ± 198 |
827 ± 216* |
847 ± 210* |
| metformin |
|
|
|
| Body mass index (kg/m2) |
23.2 ± 1.7 |
23.3 ± 1.7 |
23.5 ± 2.1 |
| Waist circumference (cm) |
87.4 ± 7.2 |
87.6 ± 7.3 |
88.2 ± 7.3 |
| HbA1c (%) |
7.5 ± 1.0 |
6.9 ± 0.8* |
6.9 ± 0.9* |
| DPP-4 (ng/mL) |
858 ± 199 |
854 ± 229 |
846 ± 216 |
Data are means ± SD. P values were calculated using Wilcoxon tests.
HbA1c: Hemoglobin A1c; DPP-4: Dipeptidyl peptidase-4.
*; p<0.05, **; p<0.01, ***; p<0.001 |
