Parameter |
NP+ND |
GD+FSD |
Pre-STZ |
Post-STZ |
6th day |
13th day |
20th day |
6th day |
13th day |
20th day |
Body weight (g) |
203.13 ± 1.25a |
222.20 ± 0.82c |
241.38 ± 1.14d |
221.88 ± 2.91c |
209.60 ± 2.38ab |
214.50 ± 1.40bc |
Food intake (g/day/rat) |
14.78 ± 0.37a |
18.76 ±0.35b |
23.16 ± 0.42c |
12.30 ± 0.36a |
18.81 ± 0.45b |
31.15 ± 1.11d |
Fasting glucose (mg/dL) |
82.70 ± 1.64a |
76.08 ± 3.34a |
64.70 ± 2.11a |
122.54 ± 1.54b |
283.17 ± 5.42c |
267.44± 9.53c |
2hr. glucose (mg/dL) |
114.70 ± 1.66b |
102.62±1.50ab |
92.32 ± 2.90a |
141.35 ± 2.51c |
372.00 ± 3.84d |
357.05 ± 9.02d |
Fasting insulin (μIU/ml) |
19.43 ± 0.54b |
20.78 ± 0.49bc |
27.12 ± 0.91d |
23.12 ± 0.35c |
14.38 ± 0.43a |
21.56 ± 0.48bc |
2hr. insulin (μIU/ml) |
22.30 ± 0.28b |
24.78 ± 0.16cd |
30.45 ± 0.46e |
26.03 ± 0.30d |
18.71 ± 0.4a |
24.25 ± 0.24c |
|
Data shown as mean ± SEM of six dams For each parameter, values with the same superscript letter are similar (non-significant, P>0.05) whereas others aren’t (significant, P<0.05). NP+ND: Normal pregnant dams received normal diet, GD+FSD: Gestational diabetic dams received fatty sucrosed diet/minimal dose of STZ (25 mg/kg b.wt.) |
Table 2(a): Female rats body weight, food intake, and serum glucose and insulin levels during the gestational period. |