Parameter NP+ND GD+FSD
Pre-STZ Post-STZ
6th day 13th day 20th day 6th day 13th day 20th day
Body weight (g) 203.13 ± 1.25a 222.20 ± 0.82c 241.38 ± 1.14d 221.88 ± 2.91c 209.60 ± 2.38ab 214.50 ± 1.40bc
Food intake (g/day/rat) 14.78 ± 0.37a 18.76 ±0.35b 23.16 ± 0.42c 12.30 ± 0.36a 18.81 ± 0.45b 31.15 ± 1.11d
Fasting glucose (mg/dL) 82.70 ± 1.64a 76.08 ± 3.34a 64.70 ± 2.11a 122.54 ± 1.54b 283.17 ± 5.42c 267.44± 9.53c
2hr. glucose (mg/dL) 114.70 ± 1.66b 102.62±1.50ab 92.32 ± 2.90a 141.35 ± 2.51c 372.00 ± 3.84d 357.05 ± 9.02d
Fasting insulin (μIU/ml) 19.43 ± 0.54b 20.78 ± 0.49bc 27.12 ± 0.91d 23.12 ± 0.35c 14.38 ± 0.43a 21.56 ± 0.48bc
2hr. insulin (μIU/ml) 22.30 ± 0.28b 24.78 ± 0.16cd 30.45 ± 0.46e 26.03 ± 0.30d 18.71 ± 0.4a 24.25 ± 0.24c
Data shown as mean ± SEM of six dams For each parameter, values with the same superscript letter are similar (non-significant, P>0.05) whereas others aren’t (significant, P<0.05). NP+ND: Normal pregnant dams received normal diet, GD+FSD: Gestational diabetic dams received fatty sucrosed diet/minimal dose of STZ (25 mg/kg b.wt.)
Table 2(a): Female rats body weight, food intake, and serum glucose and insulin levels during the gestational period.