Region/Country Population Group Genotype Allele D Frequency P-value OR (95% CI)a
I/I I/D D/D
Jiangsu/China Chinese Adults, lean BMI 18.5-23.9 566 452 82 0.28 0.019a
0.838 (0.723-0.972)a
Adults, obese BMI ≥28 463 310 47 0.25
Jiangsu/China Chinese Children BMI p20-50 204 194 53 0.33 3.1×10-4a
0.667 (0.535-0.831)a
Children BMI p>80 202 139 20 0.25
Jiangsu/China Chinese Non-diabetic 1035 814 141 0.28 0.820b
1.014 (0.870-1.147)b
T2DM 678 509 92 0.27
Beijing/China Chinese Non-diabetic 537 372 95 0.28 0.999b
1.000 (0.876-1.141)b
T2DM 555 397 97 0.28
Penisular/Malaysia Malaysian Non-diabetic 331 241 57 0.28 0.741b
0.966 (0.785-1.188)b
T2DM 295 239 50 0.29
Tests were done with an additive model; BMI: Body Mass Index; T2DM: Type 2 Diabetes; A: Adjustment for Age and Sex; B: Adjustment for Age, Sex and BMI.
Table 2: The allele D frequency of the RGS9 I/D polymorphism and its association with obesity.