Clinical characteristics                                   KK genotype P value KQ + QQ genotype P value
Control (n=168) T2DM (n=148) Control (n=82) T2DM (n=102)
Mean SD Mean SD Mean SD Mean SD
Age(years)                                            42.95 8.75 56.08 9.11 <0.001 39.82 6.39 56.16 7.87 <0.001
Age of  Onset (years) - - 47.74 10.33 - - - 44.56 7.78 -
Duration (years) - - 8.15 5.97 - - - 11.21 5.54 -
Height (cm) 156.36 8.95 162.41 9.16 <0.001 160.24 4.33 161.25 8.18 0.162
Weight (Kg) 65.19 10.47 72.12 10.34 <0.001 66.81 11.11 72.78 9.96 <0.001
Body Mass Index (Kg/m2) 24.49 4.55 28.54 4.72 <0.001 24.35 3.02 27.99 4.10 <0.001
Waist Circumference(cm) 91.56 10.73 95.60 8.48 <0.001 91.64 9.20 96.80 9.62 <0.001
Hip Circumference(cm) 96.84 9.45 98.09 10.27 0.258 93.19 7.09 101.63 10.70 <0.001
Waist Hip Ratio 0.92 0.07 0.94 0.07 <0.011 0.92 0.07 0.95 0.05 <0.001
Biceps Skinfold (mm) 10.19 4.98 13.08 6.01 <0.001 11.07 4.11 14.00 4.09 <0.001
Triceps  Skinfold (mm) 16.75 6.63 17.75 5.73 0.153 17.16 7.30 18.73 6.19 <0.040
Fasting  Glucose (mg/dL) 97.13 18.81 187.30 20.6 <0.001 98.13 10.54 173.60 25.20 <0.001
Random  Glucose (mg/dL) 127.07 25.45 214.10 22.7 <0.001 120.55 16.09 221.65 23.70 <0.001
Systolic Blood Pressure (mmHg) 120.01 11.73 138.56 9.67 <0.001 119.93 11.13 135.67 10.88 <0.001
Diastolic Blood Pressure(mmHg) 79.55 10.64 88.83 9.50 <0.001 82.41 9.37 87.73 11.66 <0.001
Pulse Rate (per minute) 75.989 9.08 80.28 9.25 <0.001 72.57 4.36 82.05 9.21 <0.001
Pulse Pressure 40.93 10.06 47.32 9.63 <0.001 40.06 9.63 46.10 10.31 <0.001
Table 2: Differences of clinical characteristics between type 2 diabetic and non-diabetic control subjects stratified by ENPP1 (K121Q) polymorphism.