Insulin Sensitivity Insulin Resistance
  Total Normal IS Low IS IR (-) IR (+)
Males          
Sample 286 77 209 222 64
Age 41.8 ± 0.9 37.1 ± 1.5 43.5 ± 1.0* 42.1 ± 1.0 40.5 ± 1.8
WC 96.1 ± 0.7 88.6 ± 1.0 98.9 ± 0.8* 93.8 ± 0.7 104.2 ± 1.6**
BMI 27.9 ± 0.5 24.9 ± 0.4 29.1 ± 0.7* 27.1 ± 0.6 30.9 ± 0.7**
WHR 0.955 ± 0.004 0.931 ± 0.006 0.964 ± 0.005* 0.951 ± 0.004 0.970 ± 0.009**
WHtR 0.572 ± 0.004 0.528 ± 0.006 0.589 ± 0.005* 0.559 ± 0.004 0.620 ± 0.010**
BF% 26.2 ± 0.4 21.2 ± 0.7 28.1 ± 0.5* 24.7 ± 0.5 31.4 ± 0.8**
FPG 106.9 ± 2.4 88.8 ± 1.3 113.6 ± 3.1* 102.2 ± 2.6 113.0 ± 5.7
Insulin 10.1 ± 0.4 4.9 ± 0.2 12.0 ± 0.4* 7.5 ± 0.2 19.0 ± 0.8**
HOMA2-IR 1.34 ± 0.05 0.64 ± 0.02 1.61 ± 0.05* 1.01 ± 0.02 2.51 ± 0.09**
QUICKI 0.342 ± 0.002 0.384 ± 0.003 0.327 ± 0.001* 0.354 ± 0.002 0.305 ± 0.002**
Females          
Sample 283 91 192 216 67
Age 41.9 ± 0.8 40.8 ± 1.4 42.4 ± 1.0 42.0 ± 0.9 41.4 ± 1.6
WC 91.0 ± 0.8 85.8 ± 1.2 93.5 ± 1.0* 88.6 ± 0.9 98.7 ± 1.7**
BMI 27.3 ± 0.3 25.3 ± 0.4 28.2 ± 0.4* 26.1 ± 0.3 31.0 ± 0.8**
WHR 0.888 ± 0.006 0.861 ± 0.008 0.901 ± 0.007* 0.884 ± 0.007 0.902 ± 0.008
WHtR 0.590 ± 0.006 0.554 ± 0.008 0.606 ± 0.007* 0.575 ± 0.006 0.638 ± 0.001**
BF% 34.3 ± 0.5 31.2 ± 0.8 35.8 ± 0.5* 33.1 ± 0.5 38.4 ± 0.9**
FPG 93.7 ± 0.7 88.0 ± 1.0 96.4 ± 0.9* 91.9 ± 0.8 99.3 ± 1.3**
Insulin 10.7 ± 0.4 5.3 ± 0.1 13.3 ± 0.5* 7.8 ± 0.2 20.2 ± 1.0**
HOMA2-IR 1.39 ± 0.05 0.68 ± 0.02 1.72 ± 0.07* 1.01 ± 0.02 2.61 ± 0.13**
QUICKI 0.344 ± 0.002 0.378 ± 0.002 0.328 ± 0.001* 0.356 ± 0.002 0.306 ± 0.002**
Values are mean ± standard error. Significance was determined by Student T Test. *p<0.05 vs. normal IS.**p<0.05 vs. IR(-) . Abbreviations: WC: Waist Circumference; BMI: Body-Mass Index; WHR: Waist-to-Hip Ratio; WHtR: Waist-to-Height ratio; BF%: Body Fat percent; FPG: Fasting Plasma Glucose; HOMA2-IR: Homeostatic Model Assessment for insulin resistance; and QUICKI: Quantitative Insulin Sensitivity Check Index.
Table 1: Clinical and Metabolic characteristics of subjects from central Mexico.