Parameter C57BL/6J BALB/c A/J S6K2-/-
Leptin, ng/ml 67.3 ± 6.2 7.8 ± 1.2 15.5 ± 2.1 35.7 ± 6.2 ***
Glucose, mg/dl 252.9 ± 14.1 231.9 ± 12.0 200.0 ± 7.1 169.0 ± 15.5 ***
Cholesterol, mg/dl 257.9 ± 8.6 144.4 ± 5.1 140.7 ± 4.0 223.0 ± 23.7
LDH, U/L 937.9 ± 114.7 391.4 ± 36.8 455.7 ± 42.3 816.0 ± 103.1
Triglycerides, mg/dl 113.6 ± 13.4 126.3 ± 13.5 141.4 ± 18.9 143.0 ± 21.9
Each value represents means ± S.E.M from groups of 8 mice.
***P<0.001 between C57BL/6 and S6K2-/- mice
Table 3: Serum chemistries of C57BL/6, BALB/c, A/J, and S6K2-/- mice at 50 weeks of age fed SD for 10 weeks followed by HFD for 40 weeks. Mice were fed ad libitum prior to collection of serum.