| Parameter |
C57BL/6J |
BALB/c |
A/J |
S6K2-/- |
| Leptin, ng/ml |
67.3 ± 6.2 |
7.8 ± 1.2 |
15.5 ± 2.1 |
35.7 ± 6.2 *** |
| Glucose, mg/dl |
252.9 ± 14.1 |
231.9 ± 12.0 |
200.0 ± 7.1 |
169.0 ± 15.5 *** |
| Cholesterol, mg/dl |
257.9 ± 8.6 |
144.4 ± 5.1 |
140.7 ± 4.0 |
223.0 ± 23.7 |
| LDH, U/L |
937.9 ± 114.7 |
391.4 ± 36.8 |
455.7 ± 42.3 |
816.0 ± 103.1 |
| Triglycerides, mg/dl |
113.6 ± 13.4 |
126.3 ± 13.5 |
141.4 ± 18.9 |
143.0 ± 21.9 |
|
| Each value represents means ± S.E.M from groups of 8 mice. |
| ***P<0.001 between C57BL/6 and S6K2-/- mice |
| Table 3: Serum chemistries of C57BL/6, BALB/c, A/J, and S6K2-/- mice at 50 weeks
of age fed SD for 10 weeks followed by HFD for 40 weeks. Mice were fed ad libitum
prior to collection of serum. |
