|
Diabetes |
Diabetes with insulin treatment |
Diabetes without insulin treatment |
Outcomes |
Estimate b(SE) |
P value |
Estimate b(SE) |
P value |
Estimate b(SE) |
P value |
MMSE Scores |
+ 0.13 (0.16) |
0.39 |
+ 0.10 (0.24) |
0.69 |
+ 0.10 (0.21) |
0.65 |
Verbal fluency |
- 0.02 (0.55) |
0.97 |
- 0.60 (0.90) |
0.51 |
+ 0.15 (0.74) |
0.83 |
Digit span |
- 0.10 (0.15) |
0.53 |
+ 0.15 (0.24) |
0.54 |
- 0.37 (0.20) |
0.07 |
WLL delayed recall |
+ 0.04 (0.12) |
0.73 |
- 0.06 (0.19) |
0.77 |
+ 0.08 (0.17) |
0.65 |
LM delayed recall |
+ 0.09 (0.43) |
0.83 |
- 0.35 (0.65) |
0.59 |
+ 0.52 (0.58) |
0.37 |
Trailmaking A |
- 4.92 (2.80) |
0.08 |
- 6.62 (4.20) |
0.12 |
- 3.81 (3.81) |
0.32 |
Trailmaking B |
- 2.23 (3.73) |
0.55 |
- 4.63 (5.43) |
0.4 |
+ 0.01 (5.02) |
1 |
Block design |
- 0.12 (0.40) |
0.77 |
+ 0.09 (0.66) |
0.89 |
- 0.21 (0.52) |
0.69 |
Plasma amylin was transformed to log10 (log10 Amylin) as a determining factor. These models were adjusted for age, gender, ethnicity, school year, ApoE4 and diabetes
duration. MMSE = Mini Mental State Exam; WLL = Word learning list; LM = Logical memory |