*significant difference versus baseline
Figure 4: Effect of metformin on HOMA-IR. HOMA-IR 5.74 ± 3.77 significantly reduced at 6 month 4.01 ± 2.13 (p=0.011), at 9 month 2.97 ± 1.49 (p<0.001) and at 1 year 2.58 ± 1.40 (p<0.001); HOMA-IR: homeostasis model assessment of insulin resistance