Studied parameter Normal weight healthy subjects (n=41) Overweight healthy subjects (n=27) Obese healthy subjects(n=40)
Fasting serum NS glucose  (mg/dl) 89.45 ± 17.04 87.81 ± 9.82 89.95 ± 13.55
Serum irisin (ng/ml) 42.76 ± 14.28 45.97 ± 6.03▲▲ 49.58 ± 7.55▲
Insulin (µIU/ml) NS 20.9 ± 8.1
(n=23)
  22.45 ± 7.1
(n=30)
Leptin (ng/ml) 23.3 ± 15.1
(n=23)
  28.9 ± 20.9●
(n=30)
ANOVA and t-test revealed, NS no significant differences in fasting glucose and insulin among the groups, ▲; t-test showed significant difference between the obese and normal weight groups (P=0.001), ▲▲; t-test revealed significant difference between overweight and normal weight groups (P=0.009), ●; t-test showed significant difference between obese and normal weight groups (P=0.001).
Table 1: Serum Irisin and related metabolic factors in healthy subjects (insulin and leptin), mean distribution values.