| Studied Parameter |
Overweight and obese healthy subjects (n=67) |
Overweight and obese T2DM patients (n=76) |
P-value |
| Age (year) |
45.88 ± 5.46 |
47.79 ± 7.51 |
NS |
| BMI (kg/m2) |
37.32 ± 5.78 |
31.67 ± 4.72 |
NS |
| Fat percentage |
38.19 ± 9.24 |
37.89 ± 8.48 |
NS |
| Irisin (ng/ml) |
48.13 ± 7.15 |
42.90 ± 11.8 |
0.001 |
| Insulin (μІu/L) |
16.84 ± 7.65 (n=30) |
20.10 ± 6.08 (n=59) |
0.04 |
| Leptin (ng/ml) |
29.30 ± 5.5 (n=30) |
42.1 ± 18.4 (n=59) |
0.001 |
| HOMA-IR |
3.7 ± 0.93 (n=30) |
7.1 ± 2.5 (n=59) |
0.001 |
|
