Studied Parameter Overweight healthy subjects (n=27) Overweight T2DM patients (n=34) Obese healthy subjects (n4=40) Obese T2DM patients (n=42) Irisin (ng/ml) 45.97 ± 6.03▲ 37.06 ± 10.89 NS 49.58 ± 7.55 NS 47.56 ± 10.49 ▲ HbA1c %   8.32 ± 2.09   6.84 ± 1.11▲ Duration of DM (month)   87.21 ± 68.10   27.21 ± 24.82▲ ANOVA and t-test revealed ▲ significant differences between obese T2DM patients and overweight T2DM patients, between overweight healthy subjects and overweight T2DM patients (P=0.001). NS: No significant differences between each of the obese healthy and overweight healthy subjects.

Table 6: Determination of the probability distribution and information about significant differences of serum irisin, HbA1c and duration of DM in diabetic patients and healthy subjects.