Studied Parameter Obese healthy subjects with < 10th irisin percentile value  (GI)(n=9) Obese healthy subjects with  irisin percentile value between 10th -90th  (GII)  (n=31) Established T2DM patients (n=76) (GIII)
Irisin  (ng/ml) 40.78 ± 0.68▲ 48.97 ± 5.20 NS 42.86 ± 11.8
Insulin  (µІu/L) 17.80 ± 5.77 NS 15.93 ± 4.74▲▲ 18.0 ± 6.08
Leptin (ng/ml) 30.73 ± 18.54 NS 24.95 ± 15.55● 42.03 ± 19.54
ANOVA and t-test showed ▲significant differences between GI and each of GII and GIII as well as between GII and GIII (P=0.002), ▲▲significant difference between GII and GIII (P=0.001), ● significant difference between GII and GIII (P=0.007). NS: No significant differences between GI and each of GII and GIII as well as between GII and GIII.
Table 7: Cut-off risk level of serum irisin for type 2 DM.