Obese healthy subjects with < 10th irisin percentile value (GI)(n=9)
Obese healthy subjects with irisin percentile value between 10th -90th (GII) (n=31)
Established T2DM patients (n=76) (GIII)
Irisin (ng/ml)
40.78 ± 0.68▲
48.97 ± 5.20 NS
42.86 ± 11.8
Insulin (µІu/L)
17.80 ± 5.77 NS
15.93 ± 4.74▲▲
18.0 ± 6.08
Leptin (ng/ml)
30.73 ± 18.54 NS
24.95 ± 15.55●
42.03 ± 19.54
ANOVA and t-test showed ▲significant differences between GI and each of GII and GIII as well as between GII and GIII (P=0.002), ▲▲significant difference between
GII and GIII (P=0.001), ● significant difference between GII and GIII (P=0.007). NS: No significant differences between GI and each of GII and GIII as well as between GII
and GIII.
Table 7: Cut-off risk level of serum irisin for type 2 DM.
