| AGT M235T |
AGT T174M |
Haplotype pair |
Control subjects (n = 230) |
Extremely obese patients (n = 335) |
|
|
| |
|
|
n |
% |
n |
% |
OR (95 %CI) |
p value |
| MM |
TT |
Hap1 Hap1 |
65 |
28.26 |
92 |
27.46 |
0.951 (0.624-1.449) |
0.816 |
| MT |
TM |
Hap1 Hap3 |
35 |
15.22 |
71 |
21.19 |
1.363 (0.835-2.226) |
0.215 |
| TT |
TT |
Hap2 Hap2 |
21 |
9.13 |
19 |
5.67 |
0.608 (0.308-1.199) |
0.151 |
| TT |
TM |
Hap2 Hap3 |
22 |
9.57 |
16 |
4.78 |
0.489 (0.242-0.985) |
0.045 |
| TT |
MM |
Hap3 Hap3 |
1 |
0.43 |
4 |
1.19 |
2.688 (0.295-24.471) |
0.380 |
|
| p=0.065 (controls vs. all extremely obese cases); haplotype pairs including Hap4 were excluded from analyses |
| Table 5a: The frequency (%) of individual haplotype pairs and odds ratio (OR) of AGT genotypes for risk of extreme obesity (Logistic Regression results with Hap1Hap2 as reference category). |
