| AGT M235T |
AGT T174M |
Haplotype pair |
Extremely obese patients |
| cases without T2DM (n = 134) |
cases with T2DM (n = 201) |
| |
|
|
n |
% |
OR (95 CI) |
p value |
n |
% |
OR (95% CI) |
p value |
| MM |
TT |
Hap1 Hap1 |
42 |
31.34 |
0.890 (0.681-1.163) |
0.393 |
50 |
24.88 |
0.788 (0.489-1.271) |
0.329 |
| MT |
TM |
Hap1 Hap3 |
28 |
20.90 |
0.800 (0.587-1.090) |
0.157 |
43 |
21.39 |
1.224 (0.715-2.094) |
0.462 |
| TT |
TT |
Hap2 Hap2 |
12 |
8.96 |
0.946 (0.635-1.411) |
0.787 |
7 |
3.48 |
0.341 (0.138-0.847) |
0.020 |
| TT |
TM |
Hap2 Hap3 |
6 |
4.48 |
1.370 (0.842-2.230) |
0.205 |
10 |
4.98 |
0.466 (0.208-1.044) |
0.063 |
| TT |
MM |
Hap3 Hap3 |
1 |
0.75 |
0.715 (0.177-2.896) |
0.639 |
3 |
1.49 |
3.073 (0.313-30.153) |
0.335 |
|
| p=0.338 (controls vs. cases without T2DM); p=0.025 (controls vs. cases with T2DM); haplotype pairs including Hap4 were excluded from analyses T2DM: Type 2 Diabetes Mellitus |
| Table 5b: The frequency (%) of individual haplotype pairs and odds ratio (OR) of AGT genotypes for risk of extreme obesity without and with T2DM . (Logistic Regression results with Hap1Hap2 as reference category). |
