AGT M235T |
AGT T174M |
Haplotype pair |
Extremely obese patients with T2DM
(n = 201) |
n |
% |
OR (95% CI) |
p value |
MM |
TT |
Hap1 Hap1 |
50 |
24.88 |
0.624 (0.360-1.084) |
0.094 |
MT |
TM |
Hap1 Hap3 |
43 |
21.39 |
0.805 (0.441-1.471) |
0.481 |
TT |
TT |
Hap2 Hap2 |
7 |
3.48 |
0.306 (0.112-0.834) |
0.021 |
TT |
TM |
Hap2 Hap3 |
10 |
4.98 |
0.874 (0.298-2.567) |
0.806 |
TT |
MM |
Hap3 Hap3 |
3 |
1.49 |
1.573 (0.159-15.583) |
0.699 |
|
p=0.191 (cases without T2DM vs. cases with T2DM)
T2DM: Type 2 Diabetes Mellitus |
Table 5c: The frequency (%) of individual haplotype pairs and odds ratio (OR) of AGT genotypes for risk of diabetes mellitus in extreme obesity. (Logistic Regression results with Hap1Hap2 as reference category). |