| |
MMSE |
Word recall |
DSST |
Stroop test |
| Immediate |
Delayed |
| HAI |
|
|
|
|
|
| Univariate analysis |
-0.284* |
-0.470**** |
-0.470**** |
-0.311* |
0.278* |
| Multivariate analysis |
|
|
|
|
|
| Model 1 |
-0.229(0.409)# |
-0.367(0.185)*** |
-0.440(0.298)*** |
-0.210(1.498) |
0.300(1.375)* |
| Model 2 |
-0.065(0.544) |
-0.406(0.246)** |
-0.503(0.390)*** |
-0.189(1.689) |
0.445(1.692)** |
| Model 3 |
-0.116(0.567) |
-0.459(0.250)** |
-0.571(0.399)*** |
-0.214(1.708) |
0.486(1.766)** |
| WBAR |
|
|
|
|
|
| Univariate analysis |
-0.263* |
-0.494**** |
-0.463**** |
-0.492**** |
0.361*** |
| Multivariate analysis |
|
|
|
|
|
| Model 1 |
-0.191(0.149) |
-0.396(0.067)*** |
-0.459(0.108)*** |
-0.442(0.505)*** |
0.453(0.482)*** |
| Model 2 |
-0.057(0.177) |
-0.366(0.081)* |
-0.453(0.128)*** |
-0.332(0.526)* |
0.372(0.560)* |
| Model 3 |
-0.071(0.197) |
-0.350(0.090)* |
-0.522(0.141)** |
-0.270(0.582)# |
0.485(0.612)** |
In the multivariate analysis cognitive function domains were used as dependent variables. Values are correlation coefficients in the univariate analysis and standardized β
coefficient (SE) in the multivariate analysis. Model 1 is adjusted for age, sex, and years of education. Model 2 is adjusted for duration of diabetes, body mass index, current
smoking, treatment modality, diastolic blood pressure, log triglycerides, uric acid, sICAM-1, log hs-CRP, log TNF-α, log IL-6, albuminuria, and eGFRcys<60ml/min/m2 in
addition to the factors in Model 1. Model 3 is adjusted for SBI, PWMLs and SWMLs in addition to the factors in Model 2. #p<0.1, *p<0.01, **p<0.01, ***p<0.005, ****p<0.001 |
