| |
T2DM and OSAS
(n=15) |
OSAS alone
(n=26) |
p value |
| Demographics |
|
|
|
| Gender (female/male) |
4/11 |
4/22 |
|
| Age (yr) |
58 ± 9 |
58± 13 |
n.s |
| Body mass index (kg/m²) |
39 ± 7 |
32 ± 5 |
<0.01 |
| Medical history |
|
|
|
| Hypertension |
14 (93) |
18 (69) |
n.s. |
| Hypercholesterolemia |
12 (80) |
10 (38) |
<0.05 |
| Coronary artery disease |
(67) |
11 (42) |
n.s. |
| Arrhythmia |
3 (20) |
4 (15) |
n.s. |
| Stroke |
2 (13) |
0 (0) |
n.s. |
| Myocardial infarction |
5 (33) |
7 (27) |
n.s. |
| COPD |
4 (19) |
2 (10) |
n.s. |
| Medication |
|
|
|
| Insulin |
8 (53) |
- |
|
| Oral antidiabetic drugs |
11 (73) |
- |
|
| Nitrates |
2 (13) |
1 (4) |
n.s. |
| β-blockers |
12 (80) |
13 (50) |
n.s. |
| Renin inhibitor |
0 (0) |
1 (4) |
n.s. |
| ACE inhibitors |
10 (67) |
7 (27) |
<0.05 |
| Angiotensin II receptor blockers |
2 (13) |
6 (23) |
n.s. |
| Diuretics |
8 (53) |
8 (31) |
n.s. |
| Calcium channel blockers |
6 (40) |
8 (31) |
n.s. |
| α-blockers |
1 (7) |
2 (8) |
n.s. |
| Cardiac and renal function |
|
|
|
| LVEF () |
60 ± 8 |
63 ± 6 |
n.s. |
| GFR (ml/min) |
144 ± 48 |
120 ± 48 |
n.s. |
| Polysomnography (baseline) |
|
|
|
| AHI (n/h) |
57 ± 18 |
48 ± 21 |
n.s. |
| Oxygen saturation nadir () |
70 ± 14 |
72 ± 13 |
n.s. |
|
| Data are presented as mean ± SD or No (%). ACE = angiotensin-converting enzyme; AHI = apnea-hypopnea-index; GFR = glomerular filtration rate; LVEF = left ventricular ejection fraction |
| Table 1: Clinical Characteristics and Sleep Parameters. |
