|
Normal glucose metabolism N=623 |
Newly-diagnosed disturbed glucose metabolism N=384 |
Pre-existent diabetes mellitus N=210 |
p-value |
Demographic data |
Age, mean (SD) in years |
59 (14) |
66 (13) |
65 (12) |
<0.001 |
Men, n (%) |
316 (51) |
202 (53) |
124 (59) |
0.112 |
Caucasian, n (%) |
492 (82) |
296 (82) |
123 (63) |
<0.001 |
Risk factors |
Hypertension*, n (%) |
263 (42) |
233 (61) |
153 (73) |
<0.001 |
Use of cholesterol-lowering drugs prior to the event, n (%) |
153 (25) |
131 (34) |
126 (60) |
<0.001 |
Atrial fibrillation, n (%) |
29 (5) |
30 (8) |
17 (8) |
0.063 |
Current smoking, n (%) |
228 (37) |
99 (26) |
48 (23) |
<0.001 |
BMI, mean (SD) in kg/m2† |
26 (3) |
27 (4) |
28 (4) |
<0.001 |
Medical history |
TIA/ischemic stroke, n (%) |
139 (22) |
102 (27) |
77 (37) |
<0.001 |
Ischemic heart disease, n (%) |
82 (13) |
69 (18) |
65 (31) |
<0.001 |
Event characteristics |
TIA, n (%) |
287 (46) |
133 (35) |
69 (33) |
<0.001 |
NIHSS, median (IQR)‡ |
2 (1-5) |
3 (1-6) |
3 (2-5) |
0.006 |
TOAST classification |
<0.001 |
Large artery disease, n (%) |
82 (13) |
94 (25) |
39 (19) |
|
Cardio-embolism, n (%) |
68 (11) |
51 (13) |
30 (14) |
|
Small vessel disease, n (%) |
131 (21) |
62 (16) |
50 (24) |
|
Other determined disease, n (%) |
47 (8) |
12 (3) |
7 (3) |
|
Undetermined disease, n (%) |
295 (47) |
165 (43) |
84 (40) |
|
Glucose assessment |
Fasting plasma glucose, mean (SD) in mmol/L |
4.9 (0.6) |
6.2 (1.4) |
7.9 (3.0) |
<0.001 |
2-hour post-load glucose, mean (SD) in mmol/L |
7.5 (2.4) |
11.2 (3.6) |
NA |
<0.001 |
Glycosylated hemoglobin, mean (SD) in mmol/mol |
36 (4) |
43 (8) |
58 (17) |
<0.001 |
|