Figure 3: RYGB effects on body weight, body composition, food intake and food choice (Cohort 4). Mice were on HFD for 12 weeks before surgery and then on breeder chow and HFD for choice after surgery. A. Body weight change in gram and percentage after surgery. The percent body weight change was calculated from baseline before surgery. B. Fat mass reduction after surgery. C. Adiposity index before and after surgery at 35 days. D. Food intake and diet preference. Calorie intake was calculated in each mouse for combined HFD and breeder chow intake. Relative preference for breeder chow vs. HFD is presented (inset). *p< 0.05 RYGB vs. sham.