| Gene Polymorphism |
Brahmins |
Guptas |
Khatris |
|
CASES |
CONTROLS |
CASES |
CONTROLS |
CASES |
CONTROLS |
ALLELE FREQ
G/A |
0.87/0.13 |
0.52/0.48 |
0.53/0.47 |
0.85/0.15 |
0.51/ 0.49 |
0.74/0.27 |
IRS 1
GENOTYPE FREQ
GG/AA/GA |
0.84/0.05/0.11 |
0.845/0.08/0.075 |
0.83/0.09/0.08 |
0.89/0.06/0.05 |
0.81/0.9/0.1 |
0.86/0.06/0.08 |
ALLELE FREQ
G/A |
0.90/0.10 |
0.88/ 0.12 |
0.87/0.13 |
0.91/0.09 |
0.86/0.14 |
0.90/0.10 |
*PI3K
GENOTYPE FREQ
GG/AA/GA |
0.48/0.46/0.055 |
0.79/0.05/0.16 |
0.52/0.35/0.13 |
0.83/0.07/0.1 |
0.49/0.47/0.04 |
0.66/0.22/0.12 |
ALLELE FREQ
G/A |
0.51/ 0.49 |
0.87/0.13 |
0.59/ 0.41 |
0.88/0.12 |
0.51/0.49 |
0.75/0.25 |
KCNJ11
GENOTYPE FREQ
GG/AA/GA |
0.91/0.025/0.06 |
0.94/0.02/0.04 |
0.84/0.07/0.09 |
0.91/0.04/0.05 |
0.92/0.03/0.05 |
0.93/0.03/0.04 |
ALLELE FREQ
G/A |
0.95/0.05 |
0.96/0.04 |
0.89/0.12 |
0.93/0.07 |
0.95/0.05 |
0.95/0.05 |
|
| * Mark indicates SNP that showed positive association with T2DM. |
| Table 1: Depiction of Allele and Genotype Frequencies of 4 Candidate Genes in 3 Caste Groups. |
