Tissues |
Groups |
Vitamin C
(µmole) |
Vitamin E
(µmole) |
TBARS
(µmole MDA) |
GSH
(µmole) |
Liver
(per 100 mg of tissue) |
PC |
10.2 ± 1.45 |
62.2 ± 0.89 |
0.268 ± 0.018 |
0.473 ± 0.076 |
PD |
4.02 ± 0.28* |
47.3 ± 1.2* |
0.581 ± 0.048* |
0.217 ± 0.015* |
CD |
8.43 ± 2.8† |
50.4 ± 1.02* |
0.407 ± 0.020*† |
0.250 ± 0.034* |
Kidney
(per 100 mg of tissue) |
PC |
8.38 ± 1.14 |
59.6 ± 0.99 |
0.222 ± 0.011 |
0.469 ± 0.052 |
PD |
2.84 ± 0.14* |
44.4 ± 0.75* |
0.526 ± 0.015* |
0.207 ± 0.032* |
CD |
7.96 ± 1.15† |
46.4 ± 0.67* |
0.362 ± 0.018*† |
0.232 ± 0.013* |
Heart
(per 100 mg of tissue) |
PC |
7.77 ± 0.84 |
55.7 ± 1.5 |
0.247 ± 0.018 |
0.444 ± 0.012 |
PD |
3.54 ± 0.28* |
42.3 ± 1.9* |
0.581 ± 0.039* |
0.215 ± 0.011* |
CD |
6.6 ± 0.39† |
46.5 ± 1.4* |
0.347 ± 0.014*† |
0.247 ± 0.013* |
Pancreas
(per 100 mg of tissue) |
PC |
7.41 ± 0.51 |
50.07 ± 0.83 |
0.237 ± 0.012 |
0.584 ± 0.036 |
PD |
3.07 ± 0.34* |
38.96 ± 0.88* |
0.450 ± 0.013* |
0.202 ± 0.013* |
CD |
4.85 ± 0.38*† |
40.76 ± 0.88* |
0.251 ± 0.012*† |
0.229 ± 0.010* |
Serum
(per ml of serum) |
PC |
8.21 ± 0.12 |
63.0 ± 0.12 |
0.262 ± 0.0036 |
22.46 ± 0.80 |
PD |
3.76 ± 0.11* |
33.3 ± 0.10* |
1.75 ± 0.0052* |
13.1 ± 1.1* |
CD |
5.10 ± 0.68*† |
47.1 ± 0.10*† |
0.584 ± 0.005*† |
19.5 ± 1.3*† |
|
The significant difference between groups for each tissue based on student t test represented by * compared to PC, † compared to PD.PC: Standard control, PD: Diabetic control, CD: Clarias oil group |
Table 3: Effect of dietary supplementation of fish oils for 30 days on tissue antioxidant and lipid peroxidation parameters in alloxan induced diabetic mice (Mus musculus).Data represented as mean of six values and their standard errors. |