DRB1 allele Siblings         n=54 (%) Controls
n=50 (%)
X2 P value OR CI
DRB1*01 6 (11.1) 10 (20) 0.97 0.33 0.5 0.38-8.12
DRB1*03 33 (61.1) 8 (16) 20.27 0.0001 8.25 2.98-23.56
DRB1*04 25 (46.29) 17 (34) 1.16 0.28 1.67 0.65-3.72
*04:01 12 (22.2) 1(2) 7.95 0.005 14 1.75-2.708
*04:02 1(1.8) 2(4) 0.05 0.95 0.45 0.02-2.77
*04:03 1(1.8) 8 (16) 3.9 0.04 0.12 0.005-0.989
*04:04 2(3.7) 1(2) 0.00 1.00 1.07 0.186*6.03
*04:05 8 (11.1) 1 (2) 2.36 0.12 4.17 0.76-30.18
*04:06 1(1.85) 3(6) 4.6 0.03 0.17 0.03-0.87
DRB1*13 6 (11.1) 17 (34) 6.6 0.01 0.243 0.076-0.747
DRB1*14 1(1.8) 4 (7.4) 1.0 0.32 0.22 0.03-1.50
DRB1*15 15 (27.8) 10 (20) 0.49 0.48 1.54 0.63-3.77
DRB1*03:01/03:01 12 (22.2) 1(2) 7.95 0.005 14.0 1.76-300.26
DRB1*03:01/04:05 8(14.8) 1(2) 3.89 0.04 8.5 1.0-188.79
X2 = chi square; OR = odds ratio; CI = confidence interval; *statistically significant
Table 1: DRB1 distribution among Siblings of T1DM and Control Subjects.