Groups       (n = 6) Serum lipid Profile (mg/dl)  
HDL Triglycerides LDL Insulin Level (μg/ml) Adiponectin levels (ng/dl)
1. Normal Control 32.11(ns) ± 21.7 87.33*** ± 2.2 90.29*** ± 12.7 16.03*** ± 0.74 7.03*** ± 2.03
2. Positive Control (DM) 20.40 ± 13.7 211.32 ± 16.3 191.78 ± 26.2 24.87 ± 0.48 1.96 ± 0.43
3.  DM + Pioglitazone 45.77(ns) ± 17.3 110.7*** ± 4.50 70.31*** ± 23.7 18.03*** ± 0.23 5.32*** ± 0.87
4. DM + Spirulina 38.57(ns) ± 19.99 175.45** ± 25.45 115** ± 27.3 23.56** ± 0.60 4.04*** ± 0.31
5. DM + Pioglitazone + Spirulina 57.4* ± 23.7 91.12*** ± 12.2 89.31*** ± 06.7 14.33*** ± 0.27 6.80*** ± 1.2
Values are given as mean ± SEM for groups of six animals each Normal group (Normal saline) Diabetic control group (Dexamethasone) ***Values are extremely significant on 21st day at ***p< 0.0001(Tukey t-test). Diabetic control group were compared with normal group. Spirulina and Pioglitazone with spirulina groups were compared with diabetic control
Table 3: Effect of Pioglitazone and Spirulina on serum lipid profile at 21st day in insulin resistance rat model.