Controls Patients P value
BMD (g/cm2) 0.47 + 0.09 0.51 + 0.09 P<0.05
BMD (z-score) 0.773 + 1.43 1.55 + 1.44 P<0.01
Serum b-ALP (U/L) 16.56 + 5.19 17.97 + 6.72     ns
Serum Osteocalcin (ng/mL) 9 + 3.8 5.6 + 2.4 P<0.0001
Urinary DpD (nm/mmol Cr) 7.7 + 3.1 8.1 + 5.2 ns
Serum b-Cross laps (nmol/L) 0.41 + 0.31 0.26 + 0.17 P<0.01
Urinary Osteomark
(nmol BCE/mM Cr)
42 (11.2 - 370)* 34.7(3.6 – 166)* P<0.05
Urinary Helical peptide (mg/mmol Cr) 48 (12.7 – 478.9)* 33.1(1.9–145.6)* P<0.01
*Values reported as median and range due to skewed distribution of analyte. Statistical
significance was assessed by unpaired Wilcoxon test
Table 2: Comparison of the Bone mineral density (BMD) and concentrations of bone turnover markers in the two study groups.