PARAMETER PATIENT 1 PATIENT 2 NORMAL RANGE
INSULIN [μ/ml] 5.1 6.9 5.0 - 15.0
PEPTIDE C [pmol/ml] 1.21 0.62 0.59 - 1.56
IAA [%] * 5.7 5.5 <5.5
GAD [U/ml] * 4.5 19.3 <1
IA2 [U/ml] * 4.1 45.4 <1
TSH [μIU/ml] 1.694 7.898 0.470-4.640
FT4 [ng/dl] 1.03 0.98 0.71-1.85
aTPO [U/ml] 0 709 <60
aTG [U/ml] 43 62 <60
• Three of recommended by IDF/ISPAD guidelines autoantibodies were measured in our patients
• Standardized assays were used to evaluate IAA, GAD and IA2 autoantibodies (RIA, DIAsource Immunoassays S.A. for IAA and RIA, EUROIMMUN Medizinische Labordiagnostika AG for GAD and IA2 evaluation). Both GAD and IA2 assays were evaluated by DASP (2005) and showed both high sensitivity and specificity (a sensitivity of 84% and 70%, and specificity of 95% and 100%, respectively) [49-51]
Table 1: Patients’ laboratory data summary.