Biomarker No. of MetS Components2
(Biomarker Mean ± SE)
P3
0 1 2 3+
Metabolic Markers

Total:HDL-C ratio
2.98 ± 0.10 3.62 ± 0.14 4.51 ± 0.13 5.25 ± 0.13 2.91x10-10
Apolipoprotein A1 (g/L) 1.57 ± 0.018 1.42 ± 0.018 1.32 ± 0.015 1.23 ± 0.018 2.22x10-8
Apolipoprotein B (g/L) 0.81 ± 0.027 0.86 ± 0.031 0.96 ± 0.032 1.03 ± 0.028 0.000047
HbA1c (%) 5.5 ± 0.1 5.6 ± 0.1 5.7 ± 0.1 5.8 ± 0.1 0.00073
Inflammatory Markers          
C-reactive protein (mg/L) 1.40 ± 0.22 2.22 ± 0.23 3.04 ± 0.24 3.91 ± 0.40 2.69x10-8
Fibrinogen (g/L) 0.029 ± 0.001 0.031 ± 0.001 0.032 ± 0.001 0.032 ± 0.002 0.00036
Homocysteine (µmol/L) 7.78 ± 0.30 7.84 ± 0.29 7.96 ± 0.27 8.12 ± 0.43 0.435
1Measures were evaluated in non-diabetic subjects aged 16 to 79 years from the Canadian Health Measures Survey
2Means are adjusted for age, sex, smoking status, physical activity levels, use of cardiovascular related medication and ethnicity
3P for trend
Table 2: Plasma levels of cardiometabolic and inflammatory markers across the metabolic syndrome components1.