Contrasts
No. of studies (cases/controls)
Homogeneous co-dominant model
Heterogeneous co-dominant model
Dominant model
Recessive model
OR
95%CI
I
2
P
H
OR
95%CI
I
2
P
H
OR
95%CI
I
2
P
H
OR
95%CI
I
2
P
H
Ethnicity
European
5 (813/943)
1.17
0.64-2.13
70.0
0.010
0.90
0.66-1.23
49.5
0.094
0.95
0.67-1.35
65.0
0.022
1.25
0.81-1.92
50.6
0.088
East Asian
4 (733/760)
1.06
0.67-1.69
55.4
0.081
1.02
0.73-1.44
50.3
0.110
1.04
0.72-1.49
60.9
0.053
1.05
0.80-1.38
17.1
0.306
South Asian
1 (120/79)
1.10
0.36-3.32
-
-
1.29
0.71-2.35
-
-
1.26
0.71-2.22
-
-
0.99
0.34-2.89
-
-
Type of DR
PDR
7 (924/1376)
1.14
0.71-1.83
68.0
0.005
0.91
0.75-1.10
34.2
0.167
0.97
0.73-1.28
56.9
0.030
1.22
0.86-1.74
53.5
0.045
NPDR
3 (267/331)
1.74
0.70-4.29
62.9
0.067
1.45
0.73-2.87
70.5
0.034
1.50
0.74-3.03
74.5
0.020
1.36
0.85-2.18
0.0
0.492
Table 4:
Pooled ORs and 95%CIs of the association between rs2010963 polymorphism in the VEGFA gene and diabetic retinopathy.