Adaptation due to oxidative stress
status |
Normal physiological OS in mother due to an increase in plasma volume, insulin resistance, inmuno-suppression and thrombophilic state. |
Same changes as in normal pre gestational weight mothers, with increased insulin resistance, possible oral glucose intolerance, increase in pro inflammatory cytokines and oxidative damage (pathologic oxidative stress). |
Same changes as in pregestational normal-weight mother; plus possible oral glucose intolerance, increase in pro inflammatory cytokines, oxidative damage (pathologic oxidative stress), and biomarkers of metabolic syndrome. Increased risk of IUGR, GDM and T2DM, PE, AHT, UTI, CAD, amongst others. |