Parameters C I+SAL I+VEGF DI+SAL DI+VEGF
LVSP (mm Hg) 134±5 113±4* 120±6* 93±4*† 94±4*‡
LVEDP (mm Hg) 5±0.3 19±2.1* 10±0.6† 14±3.2* 10±0.8
HR (bpm) 352±12 342±6 350±9 305±5*† 307±10*•
+dP/dt (mm Hg/sec) 9441± 430 4642±457* 6900±430*† 4702±325* 7207±261*‡
-dP/dt (mm Hg/sec) -7188±160 -3218±471* -5327±476*† -3523±260* 5208±245*‡
Values are expressed as mean ± SEM. LVSP – left ventricle systolic pressure; LVEDP – left ventricle end diastolic pressure; HR – heart rate; +dP/dt and –dP/dt - maximum
rate of LV pressure rise and fall. * p<0.05 vs. C; † p<0.05 vs. I+SAL; ‡ p<0.05 vs. DI+SAL; • p<0.05 vs. I+VEGF; (n=8 for each group).
Table 3: Invasive left ventricular function in control (C), myocardial infarction + saline (I+SAL), myocardial infarction + VEGF (I+VEGF), diabetes + myocardial infarction +
saline (DI+SAL), and diabetes + myocardial infarction + VEGF (DI+VEGF) groups