Gene |
Variant |
No association |
DPN
risk |
DPN protection |
Reference |
Type 1 diabetes |
NOS1 |
CA repeats |
P>0.05 |
|
|
38, 41 |
NOS2A |
CCTTT repeats |
|
|
Tendency |
38, 41 |
NOS3
|
4a/4b |
P>0.05 |
|
|
16, 38, 41 |
rs1799983
(G894T) |
P>0.05 |
|
|
38, 41 |
|
|
P<0.05
for 894T |
16, 46 |
Type 2 diabetes |
NOS2A |
AAAAT/AAAT |
|
P<0.05
for AAAAT |
|
40 |
NOS3 |
4a/4b |
|
|
P<0.05*
for 4a |
17 |
NOS3 |
rs1799983
(G894T) |
|
P<0.05
for 894T |
|
17 |
NOS1, neuronal nitric oxide synthase; NOS2A,inducible nitric oxide synthase; NOS3, endothelial nitric oxide synthase; P, significance was 0.05 or less as accepted; * obese T2DM patients |
