Histopathological changes Group Control group Lead Acetate Intoxicated Group Ajwa Extract Group Lead Acetate and Ajwa Extract Group
Group I Group II Group III Group IV
Liver        
Hepatoportal and Sinusoidal congestion - +++ - +
Cloudy swelling & Hydropic degeneration - +++ - +
Cellular necrosis (Nuclear pyknosis, karyorrhexis, karyolysis) - ++ - -/+
Inflammatory cellular infiltrate - ++ - -
Cholestasis - ++ - +
Kidneys        
Vascular congestion - +++ - +
Cloudy swelling - +++ - +
Obliteration of bowman's capsule - ++ - -
Interstitial and tubular hemorrhage - ++ - -
Focal tubular necrosis - ++ - -
Heart        
Vascular congestion - ++ - -/+
Cardiac muscle, cloudy swelling and loss of striation - ++ - +
Cardiac muscle necrosis - ++ - -
Lungs        
Congestion of alveolar capillaries - +++ - +
Edema &Thickening of alveolar wall - +++ - +
Alveolar edema (pink coagulum in lumen) - + - -
Alveolar Inflammatory cellular infiltrate - +++ - -/+
Alveolar wall destruction - ++ - -
Table 2: Histopathological scoring showing the protective effects of ethanolic extract of Ajwa Extract on rabbit organs after Lead Acetate Administration compared to other groups.