Short-term exposure to NAP
  Previtellogenic stage Vitelloginic stage
  Tel Hypo Pitu PO Tel Hypo Pitu PO
5-HT C 572.96 ± 66.53 1834.02 ± 21.81 55.77 ± 4.25 295.34 ± 3.1 491.33 ± 1.85 1351.66 ± 15.89 24.01 ± 0.55 238.78 ± 2.14
E 1108.36 ± 3.22↑ 1964.33 ± 9.79↑ 46.73 ± 1.82↓ 305.08 ± 3.62 650.44 ± 5.88↑ 1391.86 ± 4.32 22.51 ± 0.64 242.40 ± 3.06
5-HIAA C 368.6 ± 5.16 190.34 ± 3.17 41.16 ± 3.49 86.61 ± 2.40 212.43 ± 1.82 123.84 ± 4.38 7.91 ± 0.42 54.71 ± 2.21
E 334.5 ± 5.16↓ 163.13 ± 2.37↓ 28.13 ± 1.27↓ 56.35 ± 2.06↓ 217.92 ± 1.11 127.53 ± 0.26 9.86 ± 0.12 48.38 ± 1.45
DA C 185.53 ± 2.41 1645.89 ± 55.02 293.24 ± 3.56 145.87 ± 8.35 107.97 ± 1.93 996.95 ± 1.76 207.27 ± 1.70 112.33 ± 1.45
E 218.72 ± 1.15↑ 1763.96 ± 218.65 304.61 ± 7.99 183.13 ± 2.83↑ 132.34 ± 19.63 1002.28 ± 0.68 190.22 ± 5.82 117.03 ± 1.06
DOPAC C 11.66 ± 0.44 11.10 ± 0.46 34.77 ± 2.48 6.17 ± 0.72 6.56 ± 0.47 5.73 ± 0.28 13.07 ± 1.21 2.01 ± 0.04
E 14.20 ± 1.69 12.46 ± 0.75 31.86 ± 2.87 4.23 ± 0.21↑ 6.93 ± 0.23 6.66 ± 3.69 8.68 ± 0.77 2.23 ± 0.13
NA C 679.18 ± 5.52 678.69 ± 5.73 101.12 ± 1.53 230.73 ± 2.30 604.56 ± 2.73 614.33 ± 2.96 73.76 ± 2.13 198.56 ± 0.78
E 753.53 ± 97.70 695.82 ± 3.22↑ 82.28 ± 1.54↓ 229.83 ± 2.08 593.03 ± 3.02 607.13 ± 1.04 67.94 ± 2.96 193.21 ± 1.59
Tel = Telencephalon, Hypo = Hypothalamus, Pitu = Hypophysis, PO = Preoptic area
5-HT= Serotonine, 5-HIAA= 5-hydroxy-3-indoleacetic acid, DA = Dopamine, DOPAC= 3,4-dihydroxyphenylacetic acid, NA. = Noradrenalin, C= Control, E= Exposed whit NAP
↑ significantly increased in compare with control, ↓ significantly decreased in compare with control,
Table 1: Alterations of transmitter’s content in certain regions of brain in female fish exposed to NAP.