Long-term exposure to NAP
  Previtellogenic stage Vitelloginic stage
  Tel Hypo Pitu PO Tel Hypo Pitu PO
5-HT C 638.72 ± 1.54 1831.06 ± 20.72 53.96 ± 2.09 295.66 ± 3.19 489.66 ± 0.88 1351.33 ± 16.49 23.00 ± 1.10 239.23 ± 2.45
  E 579.46 ± 64.89 1787.36 ± 2.43↓ 50.88 ± 0.33 157.56 ± 19.19↓ 481.50 ± 2.27 1386.10 ± 2.41 16.43 ± 0.16 234.81 ± 0.53
5-HIAA C 370.93 ± 4.38 191.16 ± 3.72 41.32 ± 3.76 106.79 ± 2.57 213.43 ± 1.82 124.75 ± 2.27 10.97 ± 0.42 55.56 ± 1.82
E 382.24 ± 2.32 215.06 ± 2.25↑ 31.86 ± 2.44↓ 116.72 ± 3.45↑ 208.29 ± 0.37 1386.10 ± 2.41 11.92 ± 0.06 47.11 ± 4.66↓
DA C 187.56 ± 2.27 1643.43 ± 54.27 301.07 ± 1.05 145.21 ± 5.59 108.5 ± 2.21 995.56 ± 2.43 205.47 ± 1.38 114 ± 1.52
E 180.2 ± 1.01↓ 1945.06 ± 47.31↑ 304.13 ± 0.94↑ 105.66 ± 2.83↓ 104.03 ± 1.06 1520.34 ± 26.17↑ 208.60 ± 0.65 108.7 ± 0.65
DOPAC C 11.73 ± 0.31 11.28 ± 0.35 34.93 ± 1.87 6.07 ± 0.62 6.7 ± 0.34 5.98 ± 0.24 13.61 ± 0.38 2.25 ± 0.29
E 15.7 ± 0.97↑ 12.98 ± 0.17↑ 26.23 ± 2.55↑ 11.88 ± 0.50↑ 2.34 ± 0.33↓ 13.74 ± 0.75↑ 11.94 ± 0.31 1.83 ± 0.54
NA C 681.16 ± 2.02 674.92 ± 7.98 101.96 ± 1.74 233.46 ± 2.27 607.93 ± 2.26 614.00 ± 2.31 57.00 ± 1.79 200.2 ± 0.47
E 688.4 ± 1.13 754.95 ± 19.93↑ 60.69 ± 4.40↓ 232.23 ± 1.47 612.89 ± 0.37 621.49 ± 5.64 78.36 ± 1.12 202.36 ± 0.53
Tel = Telencephalon, Hypo = Hypothalamus, Pitu = Hypophysis, PO = Preoptic area
5-HT= Serotonine, 5-HIAA= 5-hydroxy-3-indoleacetic acid, DA = Dopamine, DOPAC= 3,4-dihydroxyphenylacetic acid, NA. = Noradrenalin, C= Control, E= Exposed whit NAP
↑ significantly increased in compare with control, ↓ significantly decreased in compare with control
Table 2: Alterations of transmitter’s content in certain regions of brain in female fish exposed to NAP