Parameters Experimental groups
I II III IV V
MN/2000 PCE 4.67±0.42bc 3.83±0.31b 6.50±0.43c 1.33±0.211a 8.67±0.95d
Change (fold) (+) 3.51 (+) 2.88 (+) 4.89 0.00 (+) 6.52
PCE/200 NCE 85.33±7.11bc 97.33±5.67c 67.83±3.87b 122.5±4.58a 45.5±4.19d
Change (%) (-) 30.34 (-) 20.55 (-) 44.63 0.00 (-) 62.86
Group-I, Ochratoxin A (4 ppm in feed); Group-II, Endosulfan (5 mg/kg body weight); Group-III, Ochratoxin A+ Endosulfan (4 ppm in feed + 5 mg/kg body weight); Group-IV, Control; Group-V, Cyclophosphamide (20 mg/kg body weight by interperitoneal route); Values are expressed as Mean ± SE (n = 6); Mean bearing at least one common superscript do not vary significantly between groups (P ≤ 0.01); PCE =Polychromatic Erythrocytes; NCE = Normochromatic Erythrocytes; MN=Micronuclei
Table 1: Mean values of frequency of micronuclei induced by ochratoxin A and/or endosulfan in bone marrow cells of male rats.