Experimental groups Cells scored/rat Structural chromosomal aberrations Total structure aberrations Frequency of aberrant cells(%)
Gaps Isochromatid gaps Breaks Fragments
I 312/6 9 3 9 4 25 7.05±1.55b
II 309/6 7 4 6 3 20 6.52±1.02b
III 304/6 13 4 10 7 34 11.86±0.93c
IV 302/6 2 0 1 1 4 0.99±0.44a
V 311/6 12 11 9 10 42 14.39±0.96c
Group-I, Ochratoxin A (4 ppm in feed); Group-II, Endosulfan (5 mg/kg body weight); Group-III, Ochratoxin A+ Endosulfan (4 ppm in feed + 5 mg/kg body weight); Group-IV, Control; Group-V, Cyclophosphamide (20 mg/kg body weight by interperitoneal route); Values are expressed as Mean ± SE (n = 6); Values with different superscript letters within columns represent significant statistical differences (P ≤ 0.01).
Table 2: Mean values of different chromosomal aberrations induced by ochratoxin A and/ or endosulfan in bone marrow cells of male rats.