| Treatment |
Dose /Egg (mg) |
Treatment day
hr of incubation with Cd |
Day of Sampling |
% MNE
(Mean ± SD) |
PCE:NCE |
| Control (saline) |
- |
d 12 (24 hr) |
d 13 |
0 |
0 |
| d 11 (48 hr) |
0 |
0 |
| d 10 (72 hr) |
0 |
0 |
Positive control
(Cyclophosphamide) |
50 µg |
d 12 (24 hr) |
d 13 |
1.51±0.03a |
1 |
| d 11 (48 hr) |
5.31±0.12a |
1 |
| d 10 (72 hr) |
10.17±0.10d |
1 |
| CdCl2 |
40 µg |
d 12 (24 hr) |
d 13 |
3.63±0.19b |
1.03 |
| d 11 (48 hr) |
5.43±0.28a |
1.05 |
| d 10 (72 hr) |
5.68±0.31a |
1.054 |
| CdCl2 |
50 µg |
d 12 (24 hr) |
d 13 |
5.76±0.31 c |
1.04 |
| d 11 (48 hr) |
6.81±0.09 b |
1.11 |
| d 10 (72 hr) |
7.37±0.30b |
1.07 |
| CdCl2 |
60 µg |
d 12 (24 hr) |
d 13 |
7.76±0.18d |
1.04 |
| d 11 (48 hr) |
8.60±0.16c |
1.02 |
| d 10 (72 hr) |
8.92±0.29c |
1.01 |
|
| Values are expressed as mean ± SD of 6 animals in each group. p<0.05 versus the control group; Different letters are significantly different at the level of p<0.05. MNE: Micronuclei Erythrocytes |
| Table 1: Micronucleus test performed on 13-day-old chick embryos treated with cyclophosphamide and cadmium at different time intervals |
