Geneb Control Cd Zn Cd + Zn
abcb3 0.011 ± 0.004 0.045 ± 0.011* 0.010 ± 0.003 0.03 ± 0.01
abcb3l1 0.09 ± 0.03 0.14 ± 0.03 0.14 ± 0.05 0.14 ± 0.03
abcb8 (17 ± 7).10-4 (38 ± 9).10-4 (16 ± 3).10-4 (39 ± 9).10-4
abcb9 (8 ± 2).10-4 (23 ± 10).10-4 (15 ± 3).10-4 (22 ± 4).10-4*
abcc1 0.003 ± 0.001 0.014 ± 0.003* 0.004 ± 0.002 0.016 ± 0.005*
abcc2 0.09 ± 0.05 0.25 ± 0.06 0.10 ± 0.03 0.20 ± 0.06
abcc4 0.014 ± 0.009 0.04 ± 0.01 0.009 ± 0.004 0.03 ± 0.01
abcc5 0.013 ± 0.006 0.062 ± 0.017* 0.014 ± 0.005 0.041 ± 0.008*
abcc8 (11 ± 4).10-5 (16 ± 4).10-5 (7.5 ± 2).10-5 (28 ± 6).10-5*
abcc9 0.004 ± 0.001 0.014 ± 0.003* 0.013 ± 0.006 0.034 ± 0.012*
aRelative gene expressions (mean ± SEM, n = 5). bactin1 was the reference gene.
bThe asterisk indicates a significant differential gene expression in zebrafish liver, as determined with the Mann-Whitney U-test, *p < 0.05.
Table 5: abcb and abcc gene relative expressions in liver after 7 days of metal exposurea