Muscles Gills Brain Liver Genesa Downb Upc Down Up Down Up Down Up abcb3 Znd   Znd   Znd     Cd abcb3l1 Znd         Cd     abcb7   Znd             abcb8   Znd   Cd, Znd         abcb9         Zn Cd   Cd + Zn abcb10 Znd               abcb11b Cd + Zn               abcc1 Znd     Cd       Cdd abcc2 Cd, Znd   Zn           abcc4 Znd   Znd Cd         abcc5 Cd, Znd   Znd   Cd + Zn     Cdd abcc8 Znd     Cd       Cd + Zn abcc9               Cdd aGenes abcb4, abcc6a, abcc7, and abcc12 showed no differential expression in response to metals. bDown regulation of gene as compared to control. cUp regulation of gene as compared to control. dThe same regulation was also observed in the case of the combined metal exposure.

Table 6: ABCB and ABCC transporter genes for which expression is influenced by metals after 7 days of exposure.