| Symptoms | Problems    Presentin the population | No    Problems observed | Total    Cases | P    Value | 
      
        | Hyperkeratosis    in palm and sole | 428 (28%) | 1102 (72%) | 1530 | <0.0001 | 
      
        | Melanosis    in Palm and trunk | 473 (31%) | 1057 (69%) | 1530 | <0.0001 | 
      
        | Other    skin problem – irritation | 351 (23%) | 1179 (77%) | 1530 | <0.0001 | 
      
        | Anaemia | 872 (57%) | 658 (43%) | 1530 | <0.0001 | 
      
        | Gastritis | 1315 (86%) | 215 (14%) | 1530 | <0.0001 | 
      
        | Liver    problem | 887 (58%) | 643 (42%) | 1530 | <0.0001 | 
      
        | Constipation | 596 (39%) | 934 (61%) | 1530 | <0.0001 | 
      
        | Loss    of appetite | 979 (64%) | 551 (36%) | 1530 | <0.0001 | 
      
        | Infertility    in male and female | 15 (1%) | 1515 (99%) | 1530 | <0.0001 | 
      
        | Irregular    Menstrual Cycle | 137 (9%) | 1397 (91%) | 1530 | <0.0001 | 
      
        | Asthma    or lung problem | 45 (3%) | 1485 (97%) | 1530 | <0.0001 | 
      
        | Cancer    cases | 6 (0.4%) | 1524 (99.6%) | 1530 | <0.0001 |