S. typhimurium TA98+S9 S. typhimurium TA100+S9
IQ+antimutagen(s) dose (mg/plate) No of revertants ±SD % of inhibition IQ+antimutagen(s) dose (mg/plate) No of revertans ±SD % of inhibition
0.1+0 1365 145   10+0 586 104  
0.01+0 497 166   1+0 711 79  
0.1+0.3EA 1211 194 -11 10+0.3EA 577 71 -2
0.1+3EA 1141** 157 -16 10+3 EA 579 97 -1
0.1+30EA 244** 97 -82 10+30 EA 161** 25 -73
0.1+300EA 32** 8 -98 10+300 EA 98** 17 -83
0.1+0.3CRC 1267 197 -7 10+ 0.3CRC 588 100 0
0.1+3CRC 1060** 189 -22 10+3CRC 571 128 -3
0.1+ 30CRC 528** 140 -61 10+30CRC 446* 92 -24
0.1+300CRC 18** 4 -99 10+300CRC 346** 109 -41
0.1+0.3EA+0.3CRC 1195* 180 -13 10+0.3EA+0.3CRC 595 100 +2
0.1+3EA+3CRC 1032** 192 -24 10+3EA+3CRC 465* 96 -21
0.1+30EA+30CRC 53**▼ 31 -96 10+30EA+30CRC 151** 69 -74
0.1+300EA+300CRC 23** 5 -98 10+300EA+300CRC 83** 12 -86
0.01+0.3EA 419 179 -16 1+0.3EA 619* 104 -13
0.01+3EA 416 125 -16 1+3 EA 609** 45 -14
0.01+30EA 66** 36 -87 1+ 30 EA 240** 79 -66
0.01+300EA 29** 5 -94 1+300 EA 96** 19 -87
0.01+0.3CRC 480 149 -3 1+0.3CRC 681 114 -4
0.01+3CRC 424 127 -15 1+3CRC 604** 113 -15
0.01+30CRC 187** 85 -62 1+ 30CRC 415** 79 -42
0.01+300CRC 25** 8 -95 1+300CRC 163** 45 -77
0.01+0.3EA+0.3CRC 363 175 -27 1+0.3EA+0.3CRC 585** 129 -18
0.01+3EA+3CRC 337* 148 -32 1+3EA+3CRC 514**▼ 69 -28
0.01+30EA+30CRC 32**▼ 10 -94 1+30EA+30CRC 120**▼ 22 -83
0.01+300EA+300CRC 24** 8 -95 1+300EA+300CRC 84** 9 -88
control-DMSO 28 6   control-DMSO 83 6  
SD standard deviation
*Statistically significant difference between the sample with mutagen and antimutagen(s) and the sample with specific mutagen p < 0.05
**Statistically significant difference between the sample with mutagen and antimutagen(s) and the sample with specific mutagen (1) p < 0.01
▼Statistically significant difference between the sample with combination of antimutagens and samples with specific antimutagens
Table 3: Effect of EA, CRC and their combinations on mutagenicity of IQ in Ames test.