Features

Carmustine

Lomustine

Procarbazine

Dacarbazine

Temozolomide

Chemical structure


Physical property [8]

log Kow: 1.5, solubility: 4×103 mg/L

log Kow: 2.8, solubility: 111 mg/L

log Kow: 0.1, solubility: 1.4×103 mg/L

log Kow: -0.2, solubility: 1×103 mg/L

log Kow: -0.2, solubility: 5×103 mg/L

Environmental occurrence [3, 36]

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hospital effluent: < 5ng/L

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WWTP effluent: < 0.4 ng/L*

Ecotoxicology

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Treatment strategy [20, 38, 38]

HBr in acetic acid

HBr in acetic acid

Ni-Al in KOH

Ni-Al in KOH

NaOH, H2O2

*predicted concentration in wastewater treatment plant effluent
Table 3: Summary of other alkylating agents (nitrosoureas, methylhydrazines, and tetrazines).