Intestinal causes Abnormal or increased colonic mobility
Elongated or redundant colon with long mesentery
Absence of peritoneal attachments
Malrotation or congenital malpositioning of the bowel
Gastrointestinal malignancies
Diaphragmatic/pneumonic causes Abnormally high diaphragm due to:
muscular degeneration
phrenic nerve injury
excessive aerophagia
Chronic obstructive pulmonary disease.
Changes in intrathoracic pressure [emphysema]
Pulmonary malignancies
Hepatic causes Reduced liver volume due to
cirrhosis
right lobe segmental agenesis
Liver ptosis due to relaxation/laxity of the suspensory ligaments
Miscellaneous causes Enlarged lower thoracic outlet
Elevated intra-abdominal pressure
ascites
pregnancy
High abdominal fat content/obesity
Mental retardation
Table 1: Predisposing Factors for the Development of Chilaiditi’s Sign [adapted from source: A. X.Yin [4]].