VSC evaluated Group A Group B p ppb ppb Hydrogen sulfide 7.69 ± 6.33 2.67 ± 0.73 0.444 Methyl mercaptan 289.6 ± 81.8 222.2 ± 61.6 0.549 Dimethyl sulfide 60.4 ± 10.1 62.5 ± 8.2 0.796

Table 3: Quantification of the three VSC hydrogen sulfide, methyl mercaptan and dimethyl sulfide in the breath of subjects taking PPIs since at least 3 months compared with control group at baseline (a) and at the end of treatment in Group A (b). The data are expressed in ppb as means ± Standard Error of the Mean (m ± SEM). P values are calculated using Student’s t-test. comparison between the two groups at d0 a). comparison between time zero (d0) and d15 in Group A