| Impairment due to constipation |
n |
Mean ± SD |
p-value |
| Work activity |
|
|
|
| Absenteeism, % of work time |
|
|
|
Baseline
After 2 weeks with lubiprostone
Change from baseline |
14
11
11 |
0
0
0 |
p=1 |
| Presenteeism, % impairment |
Baseline
After 2 weeks with lubiprostone
Change from baseline |
14
11
11 |
27.1 ± 33.5
17.3 ± 27.7
0.9 ± 5.1 |
p=0.297 |
| Overall productivity loss, % |
Baseline
After 2 weeks with lubiprostone
Change from baseline |
14
11
11 |
27.1 ± 33.5
17.3 ± 27.7
0.9 ± 5.1 |
p=0.297 |
| Non-work activity, % impairment |
Baseline
After 2 weeks with lubiprostone
Change from baseline |
35
28
28 |
38.6 ± 34.0
30.4 ±29.3
14.3 ± 21.6 |
p=0.002 |