Challenge viruses Spleen cells primed Pulmonary Virus Titers (log10 PFU) on Day/5
A/Bangkok/1/79(H3N2) MDP Virosome 3.3 ± 0.4
f-HANA 4.9 ± 0.6
PBS 5.1 ± 0.5
A/Philippines/2/82(H1N1) MDP Virosome 3.9 ± 0.6
f-HANA 5.0 ± 0.5
PBS 5.2 ± 0.2
A/Yamagata/120/86/(H1N1) MDP Virosome 5.2 ± 0.5
f-HANA 5.1 ± 0.7
PBS 5.3 ± 0.8
Table 1: Effect of passive transfer of immune spleen cells on the elimination of infected viruses on the lungs. Mice were infected Micro nasally with the above 3 viruses just before transfer spleen cells. Invitro secondary spleen cell stimulations were prepared from mice primed from the above 3 vaccines and transferred to recipient mice. Lung samples were collected from three group of 5 mice and the virus was titrated to MD CK cells.