| |
NF-1 associated GIST |
Sporadic GIST |
| Age |
Relatively young (<50 years) |
About 60 years |
| Gender |
Slightly female dominant |
Slightly male dominant |
| Location |
Small intestine>stomach |
Stomach (60-70%) |
| Small intestine (20-30%) |
| Colon, rectum (5%) |
| Esophagus (5%) |
| Number of tumor |
Multiple |
Solitary |
| Histology |
Spindle cell dominant |
Spindle cell (70%) |
| Epitheloid cell (20%) |
| Mixed (10%) |
| Mutation |
NF-1 |
c-KIT/PDGFRA |
| Malignant potential |
Relatively uncommon |
More common |
| Prognosis |
Good |
Relatively bad |
|