Univariate analysis (log-rank test) Multivariate analysis (Cox proportional hazards model)
Variables Statistic df P Hazard ratio 95%CI P
Sex 0.06 1 0.8004      
Age 0.20 1 0.6531      
Macro type 2.16 3 0.5404      
Site 1.65 2 0.4384      
The number of site 1.14 2 0.5641      
Depth 3.24 2 0.1978      
Histology 4.96 1 0.0260* 3.602 1.072-12.106 0.038*
Stroma 1.20 1 0.2730      
INF 0.66 2 0.7180      
ly 2.52 2 0.2836      
v 0.23 1 0.6370      
LN metastasis 4.74 2 0.0933      
Gastrectomy 2.18 1 0.1396      
New drugs 0.58 1 0.4464      
LN dissection 0.41 1 0.5202      
Tumor size 0.86 1 0.3534      
R 0.00 1 0.9537      
Liver meta (1) 0.02 1 0.8862      
Liver meta (2) 0.94 1 0.3328      
Hepatectomy 1.94 1 0.1642      
HAI 8.57 1 0.0034* 0.255 0.112-0.580 0.001*
Systemic chem. 14.82 1 0.0001* 0.239 0.093-0.612 0.003*
df degree of freedom, CI confidential interval, INF tumor infiltrative pattern, ly lymphatic invasion, v venous invasion, LN lymph node, R residual tumor , Liver meta (1) the number of metastatic nodule (solitary or multiple), Liver meta (2) the number of metastatic nodule (≤ 3 or 4 ≤), HAI hepatic arterial infusion, chem chemotherapy *P<0.05 indicates statistical significance
Table 3: Disease-specific survival in cases with only liver metastasis.