| Reported case |
Management |
Reference |
| 1. A 59 year old patient with a subcapsular hematoma of the liver with hepatic rupture secondary to amyloidosis. |
Patient died during surgery |
[7] |
| 2. A 46 year old patient with hepatic amyloidosis diagnosed premortem by liver biopsy. |
Patient died |
[8] |
| 3. A 52 year old patient with systemic amyloidosis complicated with multiple myeloma died suddenly of intraperitoneal haemorrhage due to spontaneous rupture of the spleen and liver. |
Patient died |
[9] |
| 4. A 46 year old patient with recurrent spontaneous hepatic rupture in primary amyloidosis diagnosed after surgical biopsy. |
First rupture was treated by surgery while second was treated with cyclic Melphalan and Prednisone. |
[10] |
| 5. A patient with amyloidosis complicated by reversible functional asplenia and spontaneous rupture of the liver with subcapsular hematoma. |
Hematoma resolved completely with conservative therapy. |
[11] |
| 6. A 48 year old patient case of multiple myeloma complicated by secondary systemic amyloidosis complicated by hepatic rupture. |
Treated successfully by embolization of right hepatic artery. |
[12] |
| 7. A 42 year old patient with primary amyloidosis experienced spontaneous hepatic rupture. |
Transcatheter hepatic artery embolization. |
[13] |
| 8. A case of primary systemic amyloidosis complicated by spontaneous hepatic rupture. |
Treated by surgical ligation of hepatic artery. |
[14] |
| 9. A 55-year-old woman with primary immunoglobulin light chain (AL) systemic amyloidosis died due to spontaneous rupture of her liver. |
Treatment with high-dose Melphalan (HDM) 200 mg/m2 in two divided doses, the following week and autologous stem cell transplant (HDM/SCT). Spontaneous rupture of her liver occurred 10 days after treatment with HDM/SCT and was complicated by septic shock |
[16] |
| 10. A 15-year-old boy case of hereditary autosomal dominant systemic lysosome amyloidosis, who had spontaneous hepatic rupture, underwent urgent liver transplant and survived twelve years and later died from mesenteric hemorrhage. |
Liver transplant |
[17] |
| 11. A 24-years presented with hepatic rupture confirmed by computed tomography scan. Managed initially by selective embolization and 4 weeks later underwent liver transplant. More than 2 years after presentation, she remained well despite occasional episodes of amyloid. Associated gastrointestinal haemorrhage. |
Liver transplant |
[17] |
| 12. A 34-year-old woman presented with abdominal pain and diagnosed to have hepatic rupture underwent orthotopic liver transplantation performed six days post hospitalization. She subsequently made a full recovery and reported well 4.5 years post-transplant without significant morbidity |
Liver transplant |
[18] |
| 13. A 39-year-old female with kappa light chain amyloidosis. She presented with episodes of syncope. Computerized tomography showed acute bleeding from the right lobe of the liver. Despite therapeutic efforts, the patient continued to deteriorate, requiring emergent liver transplantation. |
Liver transplant |
[19] |
